netFormulary NHS
NHS Bath and North East Somerset, Swindon and Wiltshire CCG
Royal United Hospitals Bath NHS Foundation Trust
Great Western Hospitals NHS Foundation Trust
Salisbury NHS Foundation Trust
 Search
 Formulary Chapter 14: Immunological products and vaccines - Full Chapter
Notes:

Prescribing Guidance

Please see our Prescribing Guidelines page for all prescribing guidance relating to this chapter.

Shared Care Agreements

There are no Shared Care Agreements relating to this chapter.

 

Chapter Links...
 Details...
14.04  Expand sub section  Vaccines and antisera
COVID-19 mRNA Vaccine BNT162b2 concentrate for solution for injection
(Pfizer/BioNTech COVID-19 vaccine)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunization to prevent COVID-19 disease caused by SARS-CoV-2 virus in individuals aged 16 years of age and over.
  • This is a multidose vial and must be diluted before use. 1 vial (0.45 mL) contains 6 doses of 30 micrograms of BNT162b2 RNA (embedded in lipid nanoparticles).
  • COVID-19 mRNA Vaccine BNT162b2 is administered intramuscularly after dilution as a series of two doses (0.3 mL each) at least 21 days apart.
  • Preparation: The multidose vial is stored frozen and must be thawed prior to dilution.
  • For further information see link below.
 
Link  MHRA DSU COVID-19 vaccines and medicines: updates for February 2021
Link  MHRA DSU COVID-19 vaccines and medicines: updates for March 2021
 
COVID-19 Vaccine AstraZeneca
(Solution for injection in multidose container)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines and Healthcare products Regulatory Agency. It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunisation of individuals aged 18 years and older for the prevention of coronavirus disease 2019 (COVID-19).
  • The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. The second dose should be administered between 4 and 12 weeks after the first dose.
  • COVID-19 Vaccine AstraZeneca is for intramuscular (IM) injection only, preferably in the deltoid muscle.
  • Store in a refrigerator (2 to 8°C).
  • For further information see below.
 
Link  MHRA DSU COVID-19 vaccines and medicines: updates for February 2021
Link  MHRA DSU COVID-19 vaccines and medicines: updates for March 2021
 
14.04  Expand sub section  Anthrax vaccine
14.04  Expand sub section  BCG vaccines
BCG vaccine diagnostic agent
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Tuberculline purified protein derivative (PPD) (Mantoux test) - named patient. 
 
Link  Green book chapter 32
 
BCG vaccine Intradermal
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Bacillus calmette-guerin vaccine
  • The BCG vaccine (which stands for Bacillus Calmette-Guérin vaccine) is not given as part of the routine NHS vaccination schedule. It's given on the NHS only when a child or adult is thought to have an increased risk of coming into contact with TB
 
Link  Green Book - Chapter 32
Link  NHSE items that should not be prescribed in primary care quick guide (includes some vaccines)
 
14.04  Expand sub section  Botulism antitoxin
14.04  Expand sub section  Cholera vaccine to top
Cholera vaccine
(Dukoral)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This vaccine is not indicated for most travellers
 
Link  Green Book - Chapter 14
 
14.04  Expand sub section  Diphtheria vaccines
Boostrix IPV
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Boostrix-IPV suspension for injection in pre-filled syringe
  • Diphtheria, tetanus, pertussis (acellular, component) and poliomyelitis (inactivated) vaccine (adsorbed, reduced antigen(s) content) (schedule between 3yrs & 4/12 to 5 years)
 
Link  SPS Change of maternal pertussis vaccine, Jan 2020
 
Infanrix hexa
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Powder and suspension for suspension for injection.
  • Diphtheria (D), tetanus (T), pertussis (acellular, component) (Pa), hepatitis B (rDNA) (HBV), poliomyelitis (inactivated) (IPV) and Haemophilus influenzae type b (Hib) conjugate vaccine (adsorbed).
  • Infanrix hexa is indicated for primary and booster vaccination of infants and toddlers against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis and disease caused by Haemophilus influenzae type b.
  • (schedule at 2, 3, 4 months)
 
 
Infanrix IPV
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Infanrix®-IPV, suspension for injection in pre-filled syringe
  • Diphtheria, tetanus, pertussis (acellular, component) and poliomyelitis (inactivated) vaccine (adsorbed) (schedule between 3yrs & 4/12 to 5 years)
 
 
Pediacel
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Suspension for injection in pre-filled syringe
  • Diphtheria, tetanus, pertussis (acellular, component), poliomyelitis (inactivated) and Haemophilus type b conjugate vaccine (adsorbed)
 
 
Repevax
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Suspension for injection, in pre-filled syringe
  • Diphtheria, Tetanus, Pertussis (acellular, component) and Poliomyelitis (inactivated) Vaccine (adsorbed, reduced antigen(s) content) (schedule between 3yrs & 4/12 to 5 years)
 
 
Revaxis
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Suspension for injection in pre-filled syringe
  • Diphtheria, tetanus and poliomyelitis (inactivated) vaccine (adsorbed, reduced antigen(s) content. (schedule 13-18 yrs and adults if not previously immunised)
 
 
14.04  Expand sub section  Haemophilus influenzae type B vaccine
Haemophilus influenzae type B Combined Vaccine
(Menitorix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Bath - not on formulary
 
Link  Green Book _ Chapter 16
 
14.04  Expand sub section  Hepatitis A vaccine
Hepatitis A vaccine Single Component
(Avaxim)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  Green Book - Chapter 17
 
Hepatitis A vaccine Single Component
(Havrix Monodose)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Adult and Junior
 
Link  Green Book - Chapter 17
 
Hepatitis A vaccine Single Component
(Vaqta )
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Adult and Paediatric
 
Link  Green Book - Chapter 17
 
Hepatitis A vaccine with Hepatitis B vaccine
(Ambirix )
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Hepatitis B NOT routinely available on the NHS for the purposes of travel therefore combination vaccine not commissioned locally on the NHS.
 
 
Hepatitis A vaccine with Hepatitis B vaccine
(Twinrix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Adult and Paediatric 
  • Hepatitis B NOT routinely available on the NHS for the purposes of travel therefore combination vaccine not commissioned locally on the NHS.
 
 
Hepatitis A vaccine with typhoid vaccine
(VIATIM)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
 
14.04  Expand sub section  Hepatitis B vaccine
Hepatitis B vaccine Single Component
(Engerix B)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 18
 
Hepatitis B vaccine Single Component
(Fendrix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Bath - not on formulary
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 18
 
Hepatitis B vaccine Single Component
(HBvaxPRO)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 18
 
14.04  Expand sub section  Human papilloma virus vaccine to top
Human papilloma virus vaccine
(Gardasil)
View adult BNF View SPC online
First Choice
traffic lightGreen
  • Vaccine of choice for the national immunisation program (see Green Book)
  • a quadravalent vaccine which also covers anal lesions, anal cancer and   genital warts
  • Gardasil is currently the only HPV vaccine supplied for the national HPV programme (for both adolescents and men who have sex with men).
 
14.04  Expand sub section  Influenza vaccine
 note 

Winter 2019/20 PHE Flu vaccine  

Who should have it and why? Includes information for children and pregnant women

Influenza vaccine ovalbumin content

Influenza vaccine
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Brands include: Inactivated Influenza Vaccine (Split Virion), Agrippal CSL, Inactivated Influenz Vaccine Enzira Imuvac Influvac, Fluarix Tetra, Fluad
 
Link  Green Book - Chapter 19
Link  Vaccine ordering for 2019-20 influenza season: letters
 
Influenza vaccine
(Fluenz Tetra)
(nasal)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Primary Care Only : Please note that flu vaccines for children should be ordered via IMMFORM and should NOT be reclaimed via NHS prescription services (PPA).
 
 
14.04  Expand sub section  Measles vaccine
14.04  Expand sub section  Measles, Mumps and Rubella (MMR) vaccine
Measles, Mumps and Rubella Vaccine, Live (MMR)
(MMRvaxPro Priorix)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  PHE Jan 2014: Measles, mumps, rubella (MMR): use of combined vaccine instead of single vaccines
 
14.04  Expand sub section  Meningococcal vaccines
Meningococcal polysaccharide A, C, W135 and Y vaccine
(ACWY Vax)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 22
Link  NHSE Items which should not be routinely prescribed in primary care (includes some vaccines)
 
Meningococcal A, C, W135, and Y conjugate vaccine
(Menveo)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Menveo powder and solution for solution for injection
  • Meningococcal Group A, C, W-135 and Y conjugate vaccine
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 22
Link  NHSE Items which should not be routinely prescribed in primary care (includes some vaccines)
 
Meningococcal group A, C, W-135 and Y conjugate vaccine
(Nimenrix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This vaccine is not available at NHS expense in Wiltshire/Bath/Swindon for Overseas Travel
 
Link  Green Book - Chapter 22
Link  NHSE Items which should not be routinely prescribed in primary care (includes some vaccines)
 
Meningococcal group B Vaccine
(Bexsero)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  Green Book - Chapter 22
 
Meningococcal Group C Polysaccharide Conjugate Vaccine Adsorbed
(NeisVac-C)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  Green Book- Chapter 22
 
14.04  Expand sub section  Mumps vaccine to top
14.04  Expand sub section  Pertussis vaccine
14.04  Expand sub section  Pneumococcal vaccines
23-valent pneumococcal polysaccharide vaccine
(Previously known as Pneumovax II)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Primary Care:  at NHS expense for patients in accordance with the national immunisation programme. Adults over 65 years and at risk groups, as listed in the Green Book, chapter 25.
  • Use practice stock and claim on FP34 appendix form. 
 
Link  Green Book - Chapter 25
 
Pneumococcal polysaccharide conjugate vaccine (adsorbed)
(Prevenar 13)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Primary Care:  at NHS expense for infants as part of the routine childhood immunisation programme (order free of charge via Immform)
 
Link  Green Book - Chapter 25
 
14.04  Expand sub section  Poliomyelitis vaccines
14.04  Expand sub section  Rabies vaccine
Rabies vaccine
(Rabipur)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Only on formulary for NHS use for Rabies Post-Exposure treatment in accordance with PHE guidelines. 
  • This immunisation is not remunerated by the NHS as part of additional services and is available from Private Clinics (prices may vary) if used for travel purposes (pre-exposure).  
 
Link  PHE: Guidelines on managing rabies post-exposure April 2019
 
14.04  Expand sub section  Rotavirus vaccine to top
Rotavirus vaccine
(Rotarix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Oral suspension
 
Link  Green Book - Chapter 27b
 
14.04  Expand sub section  Rubella vaccine
14.04  Expand sub section  Smallpox vaccine
14.04  Expand sub section  Tetanus vaccines
14.04  Expand sub section  Tick-borne encephalitis vaccine
Tick-borne encephalitis vaccine
(TicoVac )
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Available on a named patient basis from MASTA
  • This immunisation is not remunerated by the NHS as part of additional services and is available from Private Clinics (prices may vary).

 

 
 
14.04  Expand sub section  Typhoid vaccines to top
Polysaccharide Typhoid Vaccine
(Typherix)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  Green Book - Chapter 33
 
Polysaccharide vaccine for injection
(Typhim Vi)
View adult BNF View SPC online
Formulary
traffic lightGreen
 
Link  Green Book - Chapter 33
 
14.04  Expand sub section  Varicella-zoster vaccine
Varicella Zoster vaccine
(Zostavax)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • The aim of the national shingles immunisation programme is to lower the incidence and severity of shingles in older people. It is recommended that it be routinely offered to people aged 70 years.
  • Whilst the vaccine is authorised for use from age 50 years and is effective in this age group, the burden of shingles disease is generally not as severe in those aged 50-69 years when compared with older ages. Furthermore, given that the duration of protection is not known to last for more than ten years and the need for a second dose is not known, the vaccine is not recommended to be offered routinely below 70 years of age. Administration after 80 years of age is less cost-effective due to the limited effectiveness of the vaccine in older individuals.
 
Link  Green Book - Chapter 28a
 
Varicella-zoster vaccine
(Varilrix)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • Varilrix is indicated for active immunisation against varicella of healthy subjects (from the age of 9 months).
  • Vaccination of susceptible healthy close contacts of subjects at risk of severe varicella is recommended, in order to reduce the risk of transmission of wild-type virus to these patients. Close contacts include parents and siblings of high-risk patients, and medical and paramedical personnel.
  • Use as per green book only.
 
Link  Green Book - Chapter 34
 
Varicella-zoster vaccine
(Varivax)
View adult BNF View SPC online
Formulary
traffic lightGreen
  • VARIVAX is indicated for vaccination against varicella in individuals from 12 months of age.
  • VARIVAX can be administered to infants from 9 months of age under special circumstances, such as to conform with national vaccination schedules or in outbreak situations.
  • VARIVAX may also be administered to susceptible individuals who have been exposed to varicella. Vaccination within 3 days of exposure may prevent a clinically apparent infection or modify the course of the infection. In addition, there are limited data that indicate that vaccination up to 5 days after exposure may modify the course of the infection
  • Use as per green book only.
 
Link  Green Book - Chapter 34
 
14.04  Expand sub section  Yellow fever vaccine
Yellow fever vaccine (Live)
(Stamaril )
View adult BNF View SPC online
Formulary
traffic lightGreen
  • This immunisation is not remunerated by the NHS as part of additional services and is available from Private Clinics (prices may vary):  
 
Link  MHRA November 2019 Yellow fever vaccine: stronger precautions in people with weakened immunity and in those aged 60 years or older
Link  MHRA April 2019 - Stamaril extreme caution needed in people who may be immunosuppressed and those 60 years and older
 
 ....
 Non Formulary Items
Anthrax vaccine

View adult BNF View SPC online
Non Formulary
 
Botulism antitoxin

View adult BNF View SPC online
Non Formulary
 
Hepatitis A vaccine Single Component
(Epaxal)

View adult BNF View SPC online
Non Formulary
Green

DISCONTINUED

Link  Green Book - Chapter 17
 
Hepatitis A vaccine with typhoid vaccine
(Hepatyrix)

View adult BNF View SPC online
Non Formulary
Green

DISCONTINUED

 
Japanese Encephalitis Vaccine
(Ixiaro)

View adult BNF View SPC online
Non Formulary
  • This vaccine is not available at NHS expense in Wiltshire/Swindon/Bath for Overseas Travel.
 
Malaria vaccine
(Mosquirix)

View adult BNF View SPC online
Non Formulary
 
Meningococcal Group C Polysaccharide Conjugate Vaccine Adsorbed
(Menjugate )

View adult BNF View SPC online
Non Formulary
Green

DISCONTINUED

Link  Green Book- Chapter 22
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG
Blueteq
High Cost Drug Approval System

Traffic Light Status Information

Status Description

Traffic LightRed

RED - Hospital only to be prescribed by a specialist and supplied from secondary care ONLY throughout treatment.  

Traffic LightAmber

Amber medicines are considered suitable for GP prescribing following specialist initiation or recommendation.  

Traffic LightAmber with Shared Care

Shared Care - these medicines require specialist initiation and stabilisation. Ongoing division of responsibility for drug and disease monitoring between specialist and GP by a Shared Care Guideline (SCG). If no SCG in place status reverts to red.  

Traffic LightGreen

These medicines are appropriate for initiation in both primary and secondary care. Prescribing is appropriate within licensed or local recommendations.  

Traffic LightSelf

Suitable for patient to be directed to buy themselves  

Traffic LightGrey

Not currently used. We intend to include this TLS in future to highlight where a decision to use this medicine is under review.   

Traffic LightBlack

(In use from Oct 2020) Used where a decision has been made by the BSW APC not to routinely commission this preparation for its licensed indications. Do not prescribe.   

Traffic LightRed Specialist Centre

Not currently used. We intend to include this TLS in future to highlight where this medicine and indication is ONLY available through a Specialist Centre according to a NICE Highly Specialised Technology or NHSE Specialised Commission Circular / Policy.  

netFormulary