Dopamine receptor agonists
All other possible causes of symptoms should be excluded before prescribing for restless leg syndrome. In patients with a serum ferritin of less than 50mcg/l, prescribing oral iron supplements resolves symptoms in approx. 50% of cases.
Where all other causes have been excluded, plain ropinirole may be considered for moderate to severe idiopathic RLS. Where plain ropinirole is prescribed, the patient should be reviewed after 3 months and ropinirole discontinued if no effect has been seen.
A CCG Individual Funding Request should be made prior to initiation of any other treatment for RLS e.g. pramipexole or rotigotine.
Useful further information: BMJ Feb 2017 New concepts in the management of restless legs syndrome